Ashbel Smith Building (Old Red) – UTMB

Built in 1891 from red brick and sandstone, Old Red was the first building of the University of Texas Medical Branch — and it has outlasted almost everything thrown at it. Architect Nicholas J. Clayton designed the Romanesque Revival structure. It survived the 1900 hurricane that killed more Americans than any other natural disaster in the nation's history. Hurricane Ike put six feet of water through it in 2008. A renovation in 1985 and a Texas Historical Landmark designation in 1969 formalized what Galveston already knew: this building isn't going anywhere.